BDBM530371 WO2022064009, Compound 180b

SMILES C[C@@H]1CN([C@@H](C)c2nc(NC3CCOCC3)ncc12)C(=O)[C@H]1CCN(C)C[C@@H]1c1ccccc1

InChI Key InChIKey=JHWWIMXJPOHWHC-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 530371   

TargetCDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7(Human)
Janssen Pharmaceutica

WIPO

LigandBDBM530371(WO2022064009, Compound 180b)Copy SMILESCopy InChI

Affinity DataIC50: 2.24E+3nMAssay Description:Inhibition potencies of compounds were studied using an absorbance kinetic assay as described below. Compounds with potencies approaching the limit o...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
5/2/2022
Entry Details
Copy BDB DOIWIPO WO2022064009

Copy reaction URL