BDBM530420 WO2022064009, Compound 177a

SMILES CO[C@H]1CC[C@H](Nc2cc3c(cn2)C[C@H](C)N(C(=O)C2CCN(C)CC2c2cccc(C)c2)C3)CC1

InChI Key InChIKey=VYPXLUSXPNXRRO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 530420   

LigandChemical structure of BindingDB Monomer ID 530420BDBM530420(WO2022064009, Compound 177a)
Affinity DataIC50: 12nMAssay Description:Inhibition potencies of compounds were studied using an absorbance kinetic assay as described below. Absorbance kinetic assay (5 nM CDK7/Cyclin H/MAT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
WIPO WO2022064009

LigandChemical structure of BindingDB Monomer ID 530420BDBM530420(WO2022064009, Compound 177a)
Affinity DataIC50: 29nMAssay Description:Inhibition potencies of compounds were studied using an absorbance kinetic assay as described below. Compounds with potencies approaching the limit o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
WIPO WO2022064009