BDBM531084 US11207431, Example C

SMILES CN(c1ncc(cn1)C(=O)NO)C12CC3CC(CC(C3)C1)C2

InChI Key

Data  11 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 531084   

TargetHistone deacetylase 1(Human)
The General Hospital

US Patent
LigandPNGBDBM531084(US11207431, Example C)
Affinity DataIC50: 20nMAssay Description:IC50 measurements were conducted by BPS Biosciences (Table 1) or by Nanosyn (Table 1A) with an established fluorescence assay. More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
US Patent

TargetHistone deacetylase 3(Human)
The General Hospital

US Patent
LigandPNGBDBM531084(US11207431, Example C)
Affinity DataIC50: 24nMAssay Description:IC50 measurements were conducted by BPS Biosciences (Table 1) or by Nanosyn (Table 1A) with an established fluorescence assay. More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
US Patent

TargetPolyamine deacetylase HDAC10(Human)
The General Hospital

US Patent
LigandPNGBDBM531084(US11207431, Example C)
Affinity DataIC50: 25nMAssay Description:IC50 measurements were conducted by BPS Biosciences (Table 1) or by Nanosyn (Table 1A) with an established fluorescence assay. More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
US Patent

TargetHistone deacetylase 6(Human)
The General Hospital

US Patent
LigandPNGBDBM531084(US11207431, Example C)
Affinity DataIC50: 33nMAssay Description:IC50 measurements were conducted by BPS Biosciences (Table 1) or by Nanosyn (Table 1A) with an established fluorescence assay. More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
US Patent

TargetHistone deacetylase 4(Human)
The General Hospital

US Patent
LigandPNGBDBM531084(US11207431, Example C)
Affinity DataIC50: 34nMAssay Description:IC50 measurements were conducted by BPS Biosciences (Table 1) or by Nanosyn (Table 1A) with an established fluorescence assay. More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
US Patent

TargetHistone deacetylase 7(Human)
The General Hospital

US Patent
LigandPNGBDBM531084(US11207431, Example C)
Affinity DataIC50: 36nMAssay Description:IC50 measurements were conducted by BPS Biosciences (Table 1) or by Nanosyn (Table 1A) with an established fluorescence assay. More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
US Patent

TargetHistone deacetylase 9(Human)
The General Hospital

US Patent
LigandPNGBDBM531084(US11207431, Example C)
Affinity DataIC50: 52nMAssay Description:IC50 measurements were conducted by BPS Biosciences (Table 1) or by Nanosyn (Table 1A) with an established fluorescence assay. More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
US Patent

TargetHistone deacetylase 2(Human)
The General Hospital

US Patent
LigandPNGBDBM531084(US11207431, Example C)
Affinity DataIC50: 65nMAssay Description:IC50 measurements were conducted by BPS Biosciences (Table 1) or by Nanosyn (Table 1A) with an established fluorescence assay. More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
US Patent

TargetHistone deacetylase 5(Human)
The General Hospital

US Patent
LigandPNGBDBM531084(US11207431, Example C)
Affinity DataIC50: 121nMAssay Description:IC50 measurements were conducted by BPS Biosciences (Table 1) or by Nanosyn (Table 1A) with an established fluorescence assay. More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
US Patent

TargetHistone deacetylase 8(Human)
The General Hospital

US Patent
LigandPNGBDBM531084(US11207431, Example C)
Affinity DataIC50: 364nMAssay Description:IC50 measurements were conducted by BPS Biosciences (Table 1) or by Nanosyn (Table 1A) with an established fluorescence assay. More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
US Patent

TargetHistone deacetylase 11(Human)
The General Hospital

US Patent
LigandPNGBDBM531084(US11207431, Example C)
Affinity DataIC50: 3.60E+3nMAssay Description:IC50 measurements were conducted by BPS Biosciences (Table 1) or by Nanosyn (Table 1A) with an established fluorescence assay. More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
US Patent