BDBM531755 6-(3,5-dimethyl-1H-pyrazol-1-yl)-N-{4-ethyl-3-(4-fluorophenyl)-1-[(2-methyl-2H-tetrazol-5-yl)methyl]-1H-pyrazol-5-yl}pyrimidin-4-amine::US11208400, Example 388

SMILES O=C1CCC(N2Cc3cc(C(O)C4(O)CN(C(=O)c5ccccc5-c5ccc(Cl)cc5)C4)ccc3C2=O)C(=O)N1

InChI Key InChIKey=FJQRJBZNPKTOAT-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 531755   

TargetProtein cereblon(Human)
Gluetacs Therapeutics (Shanghai)

US Patent
LigandChemical structure of BindingDB Monomer ID 531755BDBM531755(3-(5-((1-(4'-chloro-[1,1'-biphenyl]-2- carbonyl)-3...)
Affinity DataIC50: 360nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2026
Entry Details US Patent