BDBM531773 6-(4-bromo-3,5-dimethyl-1H-pyrazol-1-yl)-N-[1-(cyclopropylmethyl)-3-(4-fluorophenyl)-4-methyl-1H-pyrazol-5-yl]pyrimidin-4-amine::US11208400, Example 406

SMILES O=C1CCC(N2Cc3cc(CN4CCCN(C(=O)c5ccccc5-c5ccc(Cl)cc5)CC4)ccc3C2=O)C(=O)N1

InChI Key InChIKey=YBNKJQMFHJHHCL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 531773   

TargetProtein cereblon(Human)
Gluetacs Therapeutics (Shanghai)

US Patent
LigandChemical structure of BindingDB Monomer ID 531773BDBM531773(3-(5-((4-(4'-chloro-[1,1'-biphenyl]-2- carbonyl)-1...)
Affinity DataIC50: 590nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2026
Entry Details US Patent