BDBM531774 N-{3-[4-(difluoromethyl)phenyl]-1,4-dimethyl-1H-pyrazol-5-yl}-6-(3,5-dimethyl-1H-pyrazol-1-yl)pyrimidin-4-amine::US11208400, Example 407

SMILES O=C1CCC(N2Cc3cc(CC4CN(Cc5ccccc5-c5ccc(Cl)cc5)C4)ccc3C2=O)C(=O)N1

InChI Key InChIKey=DYSHOAVDWFAHMO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 531774   

TargetProtein cereblon(Human)
Gluetacs Therapeutics (Shanghai)

US Patent
LigandChemical structure of BindingDB Monomer ID 531774BDBM531774(3-(5-((1-((4'-chloro-[1,1'-biphenyl]-2- yl)methyl)...)
Affinity DataIC50: 170nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2026
Entry Details US Patent