BDBM531779 N-[4-(difluoromethoxy)-5-(4-fluorophenyl)-1-methyl-1H-pyrazol-3-yl]-6-[5-(difluoromethyl)-3-methyl-1H-pyrazol-1-yl]pyrimidin-4-amine::US11208400, Example 412

SMILES O=C1CCC(N2Cc3cc(CN4CCN(Cc5ccccc5-c5cccs5)CC4)ccc3C2=O)C(=O)N1

InChI Key InChIKey=XALKWCNIAQFCLB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 531779   

TargetProtein cereblon(Human)
Gluetacs Therapeutics (Shanghai)

US Patent
LigandChemical structure of BindingDB Monomer ID 531779BDBM531779(3-(1-oxo-5-((4-(2-(thiophen-2- yl)benzyl)piperazin...)
Affinity DataIC50: 410nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2026
Entry Details US Patent