BDBM531785 US11208400, Example 418::ethyl 1-(6-{[1-(cyclopropylmethyl)-4-methyl-3-(6-methylpyridin-3-yl)-1H-pyrazol-5-yl]amino}pyrimidin-4-yl)-3,5-dimethyl-1H-pyrazole-4-carboxylate

SMILES O=C1CCC(N2Cc3cc(CN4CCN(Cc5ccc(-c6ccc[nH]6)cc5)CC4)ccc3C2=O)C(=O)N1

InChI Key InChIKey=PKFQNXBCUNLLHC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 531785   

TargetProtein cereblon(Human)
Gluetacs Therapeutics (Shanghai)

US Patent
LigandChemical structure of BindingDB Monomer ID 531785BDBM531785(3-(5-((4-(4-(1H-pyrrol-2- yl)benzyl)piperazin-1-yl...)
Affinity DataIC50: 110nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Affiliation: The Scripps Research Institute, TSRI Assay Provide...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2026
Entry Details US Patent