BDBM531800 US11208400, Example 433::tert-butyl 2-(6-{[1-(cyclopropylmethyl)-3-(4-fluorophenyl)-4-methyl-1H-pyrazol-5-yl]amino}pyrimidin-4-yl)-2,6-dihydropyrrolo[3,4-c]pyrazole-5(4H)-carboxylate

SMILES O=C1CCC(N2Cc3cc(CN4CCN(C(=O)C5=C(c6ccc(F)cc6)CCCC5)CC4)ccc3C2=O)C(=O)N1

InChI Key InChIKey=LXAVHOITUUWKBJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 531800   

TargetProtein cereblon(Human)
Gluetacs Therapeutics (Shanghai)

US Patent
LigandChemical structure of BindingDB Monomer ID 531800BDBM531800(3-(5-((4-((4'-fluoro-3,4,5,6-tetrahydro- [1,1'-bip...)
Affinity DataIC50: 460nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Affiliation: The Scripps Research Institute, TSRI Assay Provide...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2026
Entry Details US Patent