BDBM531832 6-[5-(difluoromethyl)-3-methyl-1H-pyrazol-1-yl]-N-[3-(5-fluoropyridin-2-yl)-1,4-dimethyl-1H-pyrazol-5-yl]pyrimidin-4-amine::US11208400, Example 465

SMILES CC1(C)CCC(CN2CC3CC(C2)N3Cc2cc3c(cc2F)C(=O)N(C2CCC(=O)NC2=O)C3)=C(c2ccc(Cl)cc2)C1

InChI Key InChIKey=DPMQKVOZGLFMBM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 531832   

TargetProtein cereblon(Human)
Gluetacs Therapeutics (Shanghai)

US Patent
LigandChemical structure of BindingDB Monomer ID 531832BDBM531832(3-(5-((3-((4'-chloro-5,5-dimethyl-3,4,5,6- tetrahy...)
Affinity DataIC50: 400nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Affiliation: The Scripps Research Institute, TSRI Assay Provide...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2026
Entry Details US Patent