BDBM531839 4-(1,4-dimethyl-5-{[6-(3-oxo-1,3,4,5,6,7-hexahydro-2H-indazol-2-yl)pyrimidin-4-yl]amino}-1H-pyrazol-3-yl)benzonitrile::US11208400, Example 472

SMILES O=C1CCC(N2Cc3cc(CN4CCN(Cc5ccc(-c6cccs6)cc5)CC4)ccc3C2=O)C(=O)N1

InChI Key InChIKey=DJVSSHJIQSMFCW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 531839   

TargetProtein cereblon(Human)
Gluetacs Therapeutics (Shanghai)

US Patent
LigandChemical structure of BindingDB Monomer ID 531839BDBM531839(3-(1-oxo-5-((4-(4-(thiophen-2- yl)benzyl)piperazin...)
Affinity DataIC50: 390nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Affiliation: The Scripps Research Institute, TSRI Assay Provide...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2026
Entry Details US Patent