BDBM531847 N-{1-(cyclopropylmethyl)-4-methyl-3-[4-(methylamino)phenyl]-1H-pyrazol-5-yl}-6-(3,5-dimethyl-1H-pyrazol-1-yl)pyrimidin-4-amine::US11208400, Example 480

SMILES CC1(C)CCC(CN2CC3CCC2CN3c2ccc3c(c2)C(=O)N(C2CCC(=O)NC2=O)C3=O)=C(c2ccc(Cl)cc2)C1

InChI Key InChIKey=TXHZZZWBHFZBAE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 531847   

TargetProtein cereblon(Human)
Gluetacs Therapeutics (Shanghai)

US Patent
LigandChemical structure of BindingDB Monomer ID 531847BDBM531847(5-(5-((4'-chloro-5,5-dimethyl-3,4,5,6- tetrahydro-...)
Affinity DataIC50: 110nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Affiliation: The Scripps Research Institute, TSRI Assay Provide...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2026
Entry Details US Patent