BDBM531871 N-[1-(cyclopropylmethyl)-3-(4-fluorophenyl)-4-methyl-1H-pyrazol-5-yl]-6-{4-[(�)-1-(dimethylamino)-2,2,2-trifluoroethyl]-3,5-dimethyl-1H-pyrazol-1-yl}pyrimidin-4-amine (Racemate)::US11208400, Example 504

SMILES CC1(C)CCC(CN2C3CC2CN(Cc2ccc4c(c2F)CN(C2CCC(=O)NC2=O)C4=O)C3)=C(c2ccc(Cl)cc2)C1

InChI Key InChIKey=VAMMOJPTGWXGPP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 531871   

TargetProtein cereblon(Human)
Gluetacs Therapeutics (Shanghai)

US Patent
LigandChemical structure of BindingDB Monomer ID 531871BDBM531871(3-(5-((6-((4'-chloro-5,5-dimethyl-3,4,5,6- tetrahy...)
Affinity DataIC50: 350nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Affiliation: The Scripps Research Institute, TSRI Assay Provide...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2026
Entry Details US Patent