BDBM531906 4-[3-({6-[3,5-dimethyl-4-(trifluoromethyl)-1H-pyrazol-1-yl]pyrimidin-4-yl}amino)-4-methoxy-1-methyl-1H-pyrazol-5-yl]benzonitrile::US11208400, Example 541

SMILES O=C1CCC(N2Cc3cc(CN4CC5CCC4CN5C(=O)c4ccccc4-c4ccc(Cl)cc4)ccc3C2=O)C(=O)N1

InChI Key InChIKey=GZOQQNFNDBBDMH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 531906   

TargetProtein cereblon(Human)
Gluetacs Therapeutics (Shanghai)

US Patent
LigandChemical structure of BindingDB Monomer ID 531906BDBM531906(3-(5-((5-(4'-chloro-[1,1'-biphenyl]-2- carbonyl)-2...)
Affinity DataIC50: 450nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Affiliation: The Scripps Research Institute, TSRI Assay Provide...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2026
Entry Details US Patent