BDBM533449 (Z)-9-((2R,3R,4S,5S)-5-((R)-1-(4-chloro-3- methylphenyl)-1-hydroxyethyl)-3,4- dihydroxytetrahydrofuran-2-yl)-1,9-dihydro- 6H-purin-6-one O-ethyl oxime::US11220524, Example 95

SMILES CCO/N=c1\[nH]cnc2c1ncn2[C@@H]1O[C@H]([C@](C)(O)c2ccc(Cl)c(C)c2)[C@@H](O)[C@H]1O

InChI Key InChIKey=WZVNKUZQQYTZEC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 533449   

TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Human)
Prelude Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 533449BDBM533449(US11220524, Example 95 | (Z)-9-((2R,3R,4S,5S)-5-((...)
Affinity DataIC50: 699nMAssay Description:Compounds were solubilized, and 3-fold diluted in 100% DMSO. These diluted compounds were further diluted in the assay buffer (50 mM Tris-HCl, pH 8.5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2022
Entry Details
US Patent