BDBM533458 (Z)-7-((2R,3R,4S,5R)-5-((R)-(4- chlorophenyl)(hydroxy)methyl)-3,4- dihydroxytetrahydrofuran-2-yl)-5-ethynyl- 1,7-dihydro-4H-pyrrolo[2,3-d]pyrimidin-4- one O-methyl oxime::US11220524, Example 101

SMILES C#Cc1cn([C@@H]2O[C@H]([C@H](O)c3ccc(Cl)cc3)[C@@H](O)[C@H]2O)c2[nH]cn/c(=N\OC)c12

InChI Key InChIKey=SYMWKQKVRYOYLO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 533458   

TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Human)
Prelude Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 533458BDBM533458(US11220524, Example 101 | (Z)-7-((2R,3R,4S,5R)-5-(...)
Affinity DataIC50: 308nMAssay Description:Compounds were solubilized, and 3-fold diluted in 100% DMSO. These diluted compounds were further diluted in the assay buffer (50 mM Tris-HCl, pH 8.5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2022
Entry Details
US Patent