BDBM533470 (1S,2R,3R,5R)-3-((S)-(4- chlorophenyl)(hydroxy)methyl)-5- ((E)-4-hydrazineylidene-1,4- dihydro-7H-pyrrolo[2,3- d]pyrimidin-7-yl)cyclopentane-1,2- diol::US11220524, Example 25-B

SMILES N/N=c1/nc[nH]c2c1ccn2[C@@H]1C[C@H]([C@H](O)c2ccc(Cl)cc2)[C@@H](O)[C@H]1O

InChI Key InChIKey=JKJXRCXBHKSCNR-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 533470   

TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Human)
Prelude Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 533470BDBM533470(US11220524, Example 25-B | (1S,2R,3R,5R)-3-((S)-(4...)
Affinity DataIC50: 47nMAssay Description:Compounds were solubilized, and 3-fold diluted in 100% DMSO. These diluted compounds were further diluted in the assay buffer (50 mM Tris-HCl, pH 8.5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2022
Entry Details
US Patent