BDBM534115 WO2022081807, Example 222

SMILES CC1CCN1c1cc(F)c2cc(oc2c1)C(=O)NS(=O)(=O)c1ccccc1-c1ccccc1

InChI Key InChIKey=CHLVIAYKPQFDEP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 534115   

TargetHistone acetyltransferase KAT6A [507-778](Human)
The Broad Institute

WIPO
LigandChemical structure of BindingDB Monomer ID 534115BDBM534115(WO2022081807, Example 222)
Affinity DataIC50: 129nMAssay Description:Kat6a inhibitory activities of the compounds described in the present invention were quantified using a Fluorescence Resonance Energy Transfer (TR-FR...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2022
Entry Details
WIPO WO2022081807