BDBM534125 N-([1,1'-biphenyl]-2-sulfonyl)-6-(4-fluorophenyl)-1-benzofuran-2-carboxamide ::WO2022081842, Example 1

SMILES Fc1ccc(cc1)-c1ccc2cc(oc2c1)C(=C)OS(=O)(=O)c1ccccc1-c1ccccc1

InChI Key InChIKey=HKGWUNSTHKRQFE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 534125   

TargetHistone acetyltransferase KAT6A [507-778](Human)
The Broad Institute

WIPO
LigandChemical structure of BindingDB Monomer ID 534125BDBM534125(WO2022081842, Example 1 | N-([1,1'-biphenyl]-2-sul...)
Affinity DataIC50: 3.38E+3nMAssay Description: Kat6a inhibitory activities of the compounds described in the present invention were quantified using a Fluorescence Resonance Energy Transfer (TR-F...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2022
Entry Details
WIPO WO2022081842

TargetHistone acetyltransferase KAT6B(Human)
The Broad Institute

WIPO
LigandChemical structure of BindingDB Monomer ID 534125BDBM534125(WO2022081842, Example 1 | N-([1,1'-biphenyl]-2-sul...)
Affinity DataIC50: 4.79E+3nMAssay Description: Kat6b inhibitory activities of the compounds described in the present invention were quantified using a Fluorescence Resonance Energy Transfer (TR-F...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2022
Entry Details
WIPO WO2022081842