BDBM534136 4-Methoxy-6-methyl-N-(5-methyl[1,1'-biphenyl]-2-sulfonyl)-1-benzofuran-2-carboxamide ::WO2022081842, Example 12

SMILES COc1cc(C)cc2oc(cc12)C(=O)NS(=O)(=O)c1cc(C)ccc1-c1ccccc1

InChI Key InChIKey=OOVVECAMNRMURT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 534136   

TargetHistone acetyltransferase KAT6B(Human)
The Broad Institute

WIPO
LigandChemical structure of BindingDB Monomer ID 534136BDBM534136(WO2022081842, Example 12 | 4-Methoxy-6-methyl-N-(5...)
Affinity DataIC50: 372nMAssay Description: Kat6b inhibitory activities of the compounds described in the present invention were quantified using a Fluorescence Resonance Energy Transfer (TR-F...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2022
Entry Details
WIPO WO2022081842

TargetHistone acetyltransferase KAT6A [507-778](Human)
The Broad Institute

WIPO
LigandChemical structure of BindingDB Monomer ID 534136BDBM534136(WO2022081842, Example 12 | 4-Methoxy-6-methyl-N-(5...)
Affinity DataIC50: 401nMAssay Description: Kat6a inhibitory activities of the compounds described in the present invention were quantified using a Fluorescence Resonance Energy Transfer (TR-F...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2022
Entry Details
WIPO WO2022081842