BDBM53433 2-[(4-tert-butylbenzoyl)amino]-4-(4-methoxyphenyl)-3-thenoic acid::2-[(4-tert-butylbenzoyl)amino]-4-(4-methoxyphenyl)-3-thiophenecarboxylic acid::2-[(4-tert-butylbenzoyl)amino]-4-(4-methoxyphenyl)thiophene-3-carboxylic acid::2-[(4-tert-butylphenyl)carbonylamino]-4-(4-methoxyphenyl)thiophene-3-carboxylic acid::2-[[(4-tert-butylphenyl)-oxomethyl]amino]-4-(4-methoxyphenyl)-3-thiophenecarboxylic acid::MLS001180913::Nonacylated oxime, 22::SMR000475974::US10273214, Example 1424::cid_1724256

SMILES COc1ccc(cc1)-c1csc(NC(=O)c2ccc(cc2)C(C)(C)C)c1C(O)=O

InChI Key InChIKey=ZZJMGALGEWSUIJ-UHFFFAOYSA-N

Data  4 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 53433   

TargetStreptokinase A(Streptococcus pyogenes M1 GAS)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM53433(SMR000475974 | 2-[(4-tert-butylphenyl)carbonylamin...)
Affinity DataEC50:  3.12E+3nMAssay Description:Keywords: Group A streptococcus, GAS, streptokinase, expression, virulence, inhibition, dose response, EC50 Assay Overview: The goal of this assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/8/2011
Entry Details
PCBioAssay
TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Emory University

US Patent
LigandPNGBDBM53433(SMR000475974 | 2-[(4-tert-butylphenyl)carbonylamin...)
Affinity DataIC50: 1.90E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2020
Entry Details
US Patent

TargetUbiquitin carboxyl-terminal hydrolase isozyme L1(Mouse)
Brigham and Women'S Hospital

LigandPNGBDBM53433(SMR000475974 | 2-[(4-tert-butylphenyl)carbonylamin...)
Affinity DataIC50: 2.20E+4nMpH: 7.6 T: 2°CAssay Description:Inhibition activity and selectivity for UCH-L1 and UCH-L3.More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2011
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2C(Human)
Emory University

US Patent
LigandPNGBDBM53433(SMR000475974 | 2-[(4-tert-butylphenyl)carbonylamin...)
Affinity DataIC50: 4.20E+4nMAssay Description:The assay involves using a cell line that expresses the NR1 subunit together with either NR2C or NR2D. These cell lines can be prepared by transfecti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2020
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 2D(Human)
Emory University

US Patent
LigandPNGBDBM53433(SMR000475974 | 2-[(4-tert-butylphenyl)carbonylamin...)
Affinity DataIC50: 4.30E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2020
Entry Details
US Patent