BDBM534818 4-[(1R,4S)-5-(3-fluorophenyl)- 2,5-diazabicyclo[2.2.1]hept-2-yl]- 2-isoquinolin-5-ylpyrimidine-5- carbonitrile::US11230547, Compound 1-21

SMILES Fc1cccc(c1)N1C[C@@H]2C[C@H]1CN2c1nc(ncc1C#N)-c1cccc2cnccc12

InChI Key

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 534818   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
Merck Sharp & Dohme

US Patent

LigandBDBM534818(4-[(1R,4S)-5-(3-fluorophenyl)- 2,5-diazabicyclo[2....)Copy SMILES

Affinity DataIC50: 110nMAssay Description:This assay was developed and further optimized from a kit produced by Upstate (Millipore catalog #33-047) (Millipore Sigma, Billerica Mass., USA) and...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
5/30/2022
Entry Details
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