BDBM535427 (3R)-3-(4-chlorophenyl)-4-fluoro-6-[1- hydroxy-1-(1-methyl-1H-pyrazol-4- yl)ethyl]-3-{[1- (hydroxymethyl)cyclopropyl]methoxy}- 2-[(5-methoxypyridin-2-yl)methyl]- 2,3-dihydro-1H-isoindol-1-one::US11236047, Example 224::US11236047, Example 226::US20230338337, Compound 226
SMILES COc1ccc(CN2C(=O)c3cc(cc(F)c3[C@]2(OCC2(CO)CC2)c2ccc(Cl)cc2)C(C)(O)c2cnn(C)c2)nc1
InChI Key InChIKey=FCXTWHDUAWMEGT-BDJZEIKTSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 535427
Affinity DataIC50: 0.700nMAssay Description:The ELISA assay was performed in streptavidin coated plates which were preincubated with 200 ul per well of 1 μg ml−1 biotinylated IP3 pep...More data for this Ligand-Target Pair
Affinity DataIC50: 9.5nMAssay Description:Each assay was performed in a final volume of 20 μL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning 46...More data for this Ligand-Target Pair
Affinity DataIC50: 0.700nMAssay Description:Each assay was performed in a final volume of 20 μL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning 46...More data for this Ligand-Target Pair
Affinity DataIC50: 9.5nMAssay Description:The ELISA assay was performed in streptavidin coated plates which were preincubated with 200 ul per well of 1 μg ml−1 biotinylated IP3 pep...More data for this Ligand-Target Pair