BDBM535443 (3R)-3-(4-chlorophenyl)-2-[(5- chloropyrimidin-2-yl)methyl]-4-fluoro- 6-[1-(4-fluorooxan-4-yl)-1- hydroxyethyl]-3-[(1- hydroxycyclopropyl)methoxy]-2,3- dihydro-1H-isoindol-1-one::US11236047, Example 385::US11236047, Example 386::US20230338337, Compound 386
SMILES CC(O)(c1cc2C(=O)N(Cc3ncc(Cl)cn3)[C@](OCC3(O)CC3)(c2c(F)c1)c1ccc(Cl)cc1)C1(F)CCOCC1
InChI Key InChIKey=NKWFYVHKVVJQBQ-DINWUYGQSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 535443
Affinity DataIC50: 6.10nMAssay Description:The ELISA assay was performed in streptavidin coated plates which were preincubated with 200 ul per well of 1 μg ml−1 biotinylated IP3 pep...More data for this Ligand-Target Pair
Affinity DataIC50: 0.650nMAssay Description:Each assay was performed in a final volume of 20 μL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning 46...More data for this Ligand-Target Pair
Affinity DataIC50: 6.10nMAssay Description:Each assay was performed in a final volume of 20 μL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning 46...More data for this Ligand-Target Pair
Affinity DataIC50: 0.650nMAssay Description:The ELISA assay was performed in streptavidin coated plates which were preincubated with 200 ul per well of 1 μg ml−1 biotinylated IP3 pep...More data for this Ligand-Target Pair