BDBM5355 N-(6-bromopyridin-2-yl)-5-phenyl-1,3-thiazol-2-amine::aminothiazole 15

SMILES Brc1cccc(Nc2ncc(s2)-c2ccccc2)n1

InChI Key InChIKey=NDYGPMFQINTRLH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 5355   

TargetVascular endothelial growth factor receptor 2(Human)
Merck Research Laboratories

LigandPNGBDBM5355(N-(6-bromopyridin-2-yl)-5-phenyl-1,3-thiazol-2-ami...)
Affinity DataIC50: 14nMpH: 7.4 T: 2°CAssay Description:Activated KDR was incubated with 25 uM/10 uCi of [gamma-33P] ATP, poly-Glu/Tyr, and inhibitors in kinase buffer for 15 min at 22 °C. The reactio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2005
Entry Details Article
PubMed