BDBM535738 7'-(3-((2- Chlorobenzyl)oxy)phenyl)-2'- oxo-1',4'-dihydro-2'H- spiro$#9484;pyrrolidine-3,3'- quinoline$#9488;-1-carbonitrile::US11236092, Example 18

SMILES Clc1ccccc1COc1ccccc1-c1ccc2NC(=O)C3(CCN(C3)C#N)Cc2c1

InChI Key InChIKey=TVACQTCCXVRREE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 535738   

TargetOTU domain-containing protein 7B(Human)
Mission Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 535738BDBM535738(7'-(3-((2- Chlorobenzyl)oxy)phenyl)-2'- oxo-1',4'-...)
Affinity DataIC50: 550nMAssay Description:Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2022
Entry Details
US Patent