BDBM535742 7'-(3-Methyl-1H-indazol-6-yl)- 2'-oxo-1',4'-dihydro-2'H- spiro$#9484;pyrrolidine-3,3'- quinoline$#9488;-1-carbonitrile::US11236092, Example 105::US11236092, Example 22

SMILES Cc1n[nH]c2cc(-c3ccc4c(c3)CC3(CCN(C#N)C3)C(=O)N4)ccc12

InChI Key InChIKey=IPHNXWSLDIBDAI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 535742   

TargetOTU domain-containing protein 7B(Human)
Mission Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 535742BDBM535742(7'-(3-Methyl-1H-indazol-6-yl)- 2'-oxo-1',4'-dihydr...)
Affinity DataIC50: 550nMAssay Description:Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2022
Entry Details
US Patent

TargetOTU domain-containing protein 7B(Human)
Mission Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 535742BDBM535742(7'-(3-Methyl-1H-indazol-6-yl)- 2'-oxo-1',4'-dihydr...)
Affinity DataIC50: 550nMAssay Description:Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2022
Entry Details
US Patent