BDBM535945 US11242337, Example 52

SMILES O=C1CCC(N2Cc3cc(CN4CCN(Cc5cccc(-c6ccco6)c5)CC4)ccc3C2=O)C(=O)N1

InChI Key InChIKey=HYYMDRCULIMDFM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 535945   

TargetProtein cereblon(Human)
Gluetacs Therapeutics (Shanghai)

US Patent
LigandChemical structure of BindingDB Monomer ID 535945BDBM535945(3-(5-((4-(3-(furan-2-yl)benzyl)piperazin-1- yl)met...)
Affinity DataIC50: 470nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Affiliation: The Scripps Research Institute, TSRI Assay Provide...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2026
Entry Details US Patent