BDBM5360 5-chloro-N-(pyridin-2-yl)-1,3-thiazol-2-amine::aminothiazole 20

SMILES Clc1cnc(Nc2ccccn2)s1

InChI Key InChIKey=JJZLTUWEYURFJI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 5360   

TargetVascular endothelial growth factor receptor 2(Human)
Merck Research Laboratories

LigandPNGBDBM5360(5-chloro-N-(pyridin-2-yl)-1,3-thiazol-2-amine | am...)
Affinity DataIC50: 194nMpH: 7.4 T: 2°CAssay Description:Activated KDR was incubated with 25 uM/10 uCi of [gamma-33P] ATP, poly-Glu/Tyr, and inhibitors in kinase buffer for 15 min at 22 °C. The reactio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2005
Entry Details Article
PubMed