BDBM536269 US11242344, Example 137.3

SMILES Cc1cc([C@@H](C(=O)N2C[C@H](O)C[C@H]2C2=NS(=O)(=O)CN2)C(C)C)on1

InChI Key InChIKey=ICHGUTYOUFXFKE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 536269   

Targetvon Hippel-Lindau disease tumor suppressor(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 536269BDBM536269(US11242344, Example 137.3)
Affinity DataIC50: 1.00E+5nMAssay Description:The VHL NanoBRET Target Engagement Assay analyzes the apparent affinity of test compounds for VHL in cells by competitive displacement of a VHL NanoB...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 536269BDBM536269(US11242344, Example 137.3)
Affinity DataIC50: 4.00E+5nMAssay Description:The binding of test compounds to the VHL Elongin B/C complex was measured using a fluorescence polarization tracer competition assay. The VHL/Elongin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2022
Entry Details
US Patent