BDBM536302 2-(2-ethoxy-5-((4-methylpiperazin-1-yl)sulfonyl)phenyl)-6-(hydroxymethyl)-5-methyl-7-propylpyrrolo[2,1-f][1,2,4]triazin-4(3H)-one::US11242347, Compound 1b::US11897890, Compound lb

SMILES CCCc1c(CO)c(C)c2n1nc([nH]c2=O)-c1cc(ccc1OCC)S(=O)(=O)N1CCN(C)CC1

InChI Key InChIKey=RAMVZSUODCDFFW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 536302   

TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Topadur Pharma

US Patent
LigandPNGBDBM536302(2-(2-ethoxy-5-((4-methylpiperazin-1-yl)sulfonyl)ph...)
Affinity DataIC50: 12nMAssay Description:Purpose: Evaluation of the effects of compounds of the present invention on the activity of the human phosphodiesterase-5 quantified by measuring the...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2025
Entry Details
US Patent

TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Topadur Pharma

US Patent
LigandPNGBDBM536302(2-(2-ethoxy-5-((4-methylpiperazin-1-yl)sulfonyl)ph...)
Affinity DataIC50: 12nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2022
Entry Details
US Patent

TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Topadur Pharma

US Patent
LigandPNGBDBM536302(2-(2-ethoxy-5-((4-methylpiperazin-1-yl)sulfonyl)ph...)
Affinity DataIC50: 12nMAssay Description:Experimental protocol: The test compound, i.e the compound of the present invention, reference compound or water (control) are added to a buffer cont...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
US Patent