BDBM537162 US11247989, Example 142

SMILES CC(=O)N1CCc2c(c(C3=CNC4N=CC(C(F)(F)F)=CC34)nn2C2CCOCC2)C1

InChI Key InChIKey=MIYGFHVUZQNCHN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 537162   

TargetCREB-binding protein(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 537162BDBM537162(US11247989, Example 142)
Affinity DataIC50: 42.3nMAssay Description:His/Flag epitope tagged CBP was cloned, expressed, and purified to homogeneity. CBP binding and inhibition was assessed by monitoring the engagement ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2022
Entry Details
US Patent