BDBM538044 4-(3-(1-(cyclopentanecarbonyl)-4-oxido-1,4-azaphosphinan-4-yl)-44-fluorobenzyl)phthalazin-1(2H)-one::US11248013, Example 2

SMILES O=C(C1CCCC1)N1CCP(=O)(c2cc(Cc3n[nH]c(=O)c4ccccc34)ccc2F)CC1

InChI Key InChIKey=VRMUFOYCHGHIQR-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 538044   

TargetPoly [ADP-ribose] polymerase 1(Human)
Rakovina Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 538044BDBM538044(4-(3-(1-(cyclopentanecarbonyl)-4-oxido-1,4-azaphos...)
Affinity DataIC50: 5.50E+3nMAssay Description:Inhibition of PARP-1 enzymatic activities was measured using an HT Universal Colorimetric PARP Assay Kit (Trevigen, catalogue #4677-096-K) following ...More data for this Ligand-Target Pair
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Date in BDB:
6/13/2022
Entry Details
US Patent