BDBM540214 US11261186, Example 140

SMILES C[C@@H]1C[C@H](n2cc(-n3cc(-c4cnn5ccc(N6CCOCC6)nc45)nn3)c(C(F)F)n2)CCN1

InChI Key InChIKey=GVRXAIQMGKZIBB-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 540214   

TargetInterleukin-1 receptor-associated kinase 4(Human)
Shenzhen Zhongge Biological Technology

US Patent
LigandChemical structure of BindingDB Monomer ID 540214BDBM540214(4-(3-(1-(3-(difluoromethyl)-1-((2R,4R)-2-methylpip...)
Affinity DataIC50: 100nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2026
Entry Details US Patent