BDBM540218 US11261186, Example 144

SMILES C[C@H]1COCCN1c1ccn2ncc(-c3cn(-c4cn(C5CCCCC5)nc4C(F)F)nn3)c2n1

InChI Key InChIKey=ZVERGCSRTNDVED-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 540218   

TargetInterleukin-1 receptor-associated kinase 4(Human)
Shenzhen Zhongge Biological Technology

US Patent
LigandChemical structure of BindingDB Monomer ID 540218BDBM540218((S)-4-(3-(1-(1-cyclohexyl-3-(difluoromethyl)-1H-py...)
Affinity DataIC50: 550nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2026
Entry Details US Patent