BDBM540227 US11261186, Example 154

SMILES O=S1(=O)CCN(c2ccn3ncc(-c4cn(-c5cn(C6CCC(CO)CC6)nc5C(F)F)nn4)c3n2)CC1

InChI Key InChIKey=MGKSLKHLVFRVRA-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 540227   

TargetInterleukin-1 receptor-associated kinase 4(Human)
Shenzhen Zhongge Biological Technology

US Patent
LigandChemical structure of BindingDB Monomer ID 540227BDBM540227(4-(3-(1-(3-(difluoromethyl)-1-(4-(methylol)cyclohe...)
Affinity DataIC50: 550nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2026
Entry Details US Patent