BDBM540305 US11261186, Example 233

SMILES Fc1ccc2c(c1)[C@H]1CCCN1c1ccc3ncc(n3n1)-c1cc(ncn1)CO2

InChI Key InChIKey=CMTBJUBMHQRXGK-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 540305   

TargetHigh affinity nerve growth factor receptor(Human)
Suzhou Langrui Biopharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 540305BDBM540305((14bR,E)-13-fluoro-14b,15,16,17-tetrahydro-9H-1,19...)
Affinity DataIC50: 3nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Affiliation: UT Southwestern Assay Provider: David Mangelsdorf,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2026
Entry Details US Patent

TargetHigh affinity nerve growth factor receptor NTRK1 [F589L](Homo sapiens (Human))
Suzhou Langrui Biopharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 540305BDBM540305((14bR,E)-13-fluoro-14b,15,16,17-tetrahydro-9H-1,19...)
Affinity DataIC50: 5nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Affiliation: UT Southwestern Assay Provider: David Mangelsdorf,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2026
Entry Details US Patent