BDBM540351 US11261186, Example 282

SMILES O=C1CC[C@H](NC(=O)c2ccc3c(n2)OC[C@H]2CN(CC4CCN(c5ccc([C@@H]6c7ccc(O)cc7CC[C@@H]6c6ccccc6)cc5)CC4)CCN32)C(=O)N1

InChI Key InChIKey=JXQNRPHEEFFAJJ-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 540351   

TargetEstrogen receptor [282-595](Homo sapiens (Human))
Regent Of The University Of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 540351BDBM540351((4aR)-N-(2,6-dioxopiperidin- 3-yl)-3-((1-(4-((1R,2...)
Affinity DataIC50: 10nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Affiliation: UT Southwestern Assay Provider: David Mangelsdorf,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2026
Entry Details US Patent

TargetDNA damage-binding protein 1/Protein cereblon(Human)
Regent Of The University Of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 540351BDBM540351((4aR)-N-(2,6-dioxopiperidin- 3-yl)-3-((1-(4-((1R,2...)
Affinity DataIC50: 2.75E+3nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Affiliation: UT Southwestern Assay Provider: David Mangelsdorf,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2026
Entry Details US Patent