BDBM540369 US11261186, Example 300

SMILES COc1cc(N2CCC(CN3CCN4c5ccc6c(c5OC[C@H]4C3)CN([C@H]3CCC(=O)NC3=O)C6=O)CC2)ccc1[C@@H]1c2ccc(O)cc2CC[C@@H]1c1ccccc1

InChI Key InChIKey=WDGWVVNNTBUICI-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 540369   

TargetEstrogen receptor [282-595](Homo sapiens (Human))
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US Patent
LigandChemical structure of BindingDB Monomer ID 540369BDBM540369((R)-3-((S)-7-((1-(4-((1R,2R)- 6-hydroxy-2-phenyl-1...)
Affinity DataIC50: 10nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Affiliation: UT Southwestern Assay Provider: David Mangelsdorf,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2026
Entry Details US Patent

TargetDNA damage-binding protein 1/Protein cereblon(Human)
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US Patent
LigandChemical structure of BindingDB Monomer ID 540369BDBM540369((R)-3-((S)-7-((1-(4-((1R,2R)- 6-hydroxy-2-phenyl-1...)
Affinity DataIC50: 275nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Affiliation: UT Southwestern Assay Provider: David Mangelsdorf,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2026
Entry Details US Patent