BDBM540370 US11261186, Example 301

SMILES O=C1CC[C@H](N2Cc3cc4c(cc3C2=O)OCC42CCN(C[C@@H]3COC4(CCN(c5ccc([C@H]6c7ccc(O)cc7CC[C@H]6c6ccccc6)cc5)CC4)C3)CC2)C(=O)N1

InChI Key InChIKey=GKVXVDTUIUTYHB-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 540370   

TargetEstrogen receptor [282-595](Homo sapiens (Human))
Regent Of The University Of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 540370BDBM540370((3S)-3-((5aR)-7-((2-(4-((1S, 2R)-6-hydroxy-2-pheny...)
Affinity DataIC50: 10nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Affiliation: UT Southwestern Assay Provider: David Mangelsdorf,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2026
Entry Details US Patent

TargetDNA damage-binding protein 1/Protein cereblon(Human)
Regent Of The University Of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 540370BDBM540370((3S)-3-((5aR)-7-((2-(4-((1S, 2R)-6-hydroxy-2-pheny...)
Affinity DataIC50: 275nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Affiliation: UT Southwestern Assay Provider: David Mangelsdorf,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2026
Entry Details US Patent