BDBM540419 US11261186, Example 350

SMILES O=C1CC[C@H](N2Cc3cc4c(cc3C2=O)OC[C@@H]2CN(C[C@@H]3COC5(C3)CN(c3ccc([C@@H]6c7ccc(O)cc7CC[C@@H]6c6ccccc6)cc3)C5)CCN42)C(=O)N1

InChI Key InChIKey=KXDFOTREEYMGBM-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 540419   

TargetEstrogen receptor [282-595](Homo sapiens (Human))
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US Patent
LigandChemical structure of BindingDB Monomer ID 540419BDBM540419((S)-3-((S)-3-(((R)-2-(4-((1R,2S)- 6-hydroxy-2-phen...)
Affinity DataIC50: 10nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Affiliation: UT Southwestern Assay Provider: David Mangelsdorf,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2026
Entry Details US Patent

TargetDNA damage-binding protein 1/Protein cereblon(Human)
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US Patent
LigandChemical structure of BindingDB Monomer ID 540419BDBM540419((S)-3-((S)-3-(((R)-2-(4-((1R,2S)- 6-hydroxy-2-phen...)
Affinity DataIC50: 2.75E+3nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Affiliation: UT Southwestern Assay Provider: David Mangelsdorf,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2026
Entry Details US Patent