BDBM540460 US11261186, Example 396

SMILES O=C1CC[C@H](N2Cc3c(ccc4c3OCC43CCN(CC4CC5(CCN(c6ccc([C@@H]7c8ccc(O)cc8CC[C@@H]7c7ccccc7)cn6)CC5)C4)CC3)C2=O)C(=O)N1

InChI Key InChIKey=AKXDUAWIQYHZQM-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 540460   

TargetEstrogen receptor [282-595](Homo sapiens (Human))
Regent Of The University Of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 540460BDBM540460((S)-3-(1'-((7-(5-((1S,2S)-6- hydroxy-2-phenyl-1,2,...)
Affinity DataIC50: 10nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Affiliation: UT Southwestern Assay Provider: David Mangelsdorf,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2026
Entry Details US Patent

TargetDNA damage-binding protein 1/Protein cereblon(Human)
Regent Of The University Of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 540460BDBM540460((S)-3-(1'-((7-(5-((1S,2S)-6- hydroxy-2-phenyl-1,2,...)
Affinity DataIC50: 50nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Affiliation: UT Southwestern Assay Provider: David Mangelsdorf,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2026
Entry Details US Patent