BDBM540495 US11261186, Example 431

SMILES O=C1CC[C@H](N2Cc3c(ccc4c3OCC43CCN(CC4CCC5(CC4)CN(c4ncc([C@@H]6c7ccc(O)cc7CC[C@@H]6c6ccccc6)cn4)C5)CC3)C2=O)C(=O)N1

InChI Key InChIKey=KBCLMIXXGZNWJT-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 540495   

TargetEstrogen receptor [282-595](Homo sapiens (Human))
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US Patent
LigandChemical structure of BindingDB Monomer ID 540495BDBM540495((S)-3-(1'-((2-(5-((1S,2S)-6- hydroxy-2-phenyl-1,2,...)
Affinity DataIC50: 10nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Affiliation: UT Southwestern Assay Provider: David Mangelsdorf,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2026
Entry Details US Patent

TargetDNA damage-binding protein 1/Protein cereblon(Human)
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US Patent
LigandChemical structure of BindingDB Monomer ID 540495BDBM540495((S)-3-(1'-((2-(5-((1S,2S)-6- hydroxy-2-phenyl-1,2,...)
Affinity DataIC50: 50nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Affiliation: UT Southwestern Assay Provider: David Mangelsdorf,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2026
Entry Details US Patent