BDBM540510 US11261186, Example 446

SMILES COc1cc(N2CCC3(CC2)C[C@H](CN2CCN4c5cc6c(cc5OC[C@@H]4C2)C(=O)N([C@H]2CCC(=O)NC2=O)C6)CO3)c(F)cc1[C@@H]1c2ccc(O)cc2CC[C@@H]1c1ccccc1

InChI Key InChIKey=VFMXNNMLVZMDLQ-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 540510   

TargetEstrogen receptor [282-595](Homo sapiens (Human))
Regent Of The University Of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 540510BDBM540510((S)-3-((S)-3-(((R)-8-(2-fluoro-4- ((1S,2S)-6-hydro...)
Affinity DataIC50: 10nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Affiliation: UT Southwestern Assay Provider: David Mangelsdorf,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2026
Entry Details US Patent