BDBM540514 US11261186, Example 450

SMILES CC%10(C)CC(c1ccc(Cl)cc1)=C9CN8CCN(c7ccc(C(=O)NS(=O)(=O)c3ccc(NCC2CCOCC2)c([N+](=O)[O-])c3)c(N6CCCOc5nc4[nH]ccc4cc56)c7)C[C@H]8COCCCO[C@@H]9C%10

InChI Key InChIKey=IOIZINQATQTQGO-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 540514   

TargetApoptosis regulator Bcl-2(Human)
Abbvie

US Patent
LigandChemical structure of BindingDB Monomer ID 540514BDBM540514(US20260028356, Example 1)
Affinity DataKi:  0.459nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Affiliation: UT Southwestern Assay Provider: David Mangelsdorf,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2026
Entry Details US Patent

TargetBcl-2-like protein 1(Human)
Abbvie

US Patent
LigandChemical structure of BindingDB Monomer ID 540514BDBM540514(US20260028356, Example 1)
Affinity DataKi:  19.4nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Affiliation: UT Southwestern Assay Provider: David Mangelsdorf,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2026
Entry Details US Patent