BDBM540528 US11261186, Example 464

SMILES CC%11(C)CC(c1ccc(Cl)cc1)=C%10CN9CCN(c8ccc(C(=O)NS(=O)(=O)c4ccc(NCC3CC(O)(C2CCC2)C3)c([N+](=O)[O-])c4)c(N7CCCOc6nc5[nH]ccc5cc67)c8)C[C@H]9COCCCO[C@@H]%10C%11

InChI Key InChIKey=RAGLZVSCKHCJPL-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 540528   

TargetApoptosis regulator Bcl-2(Human)
Abbvie

US Patent
LigandChemical structure of BindingDB Monomer ID 540528BDBM540528(US20260028356, Example 15)
Affinity DataKi:  0.552nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Affiliation: UT Southwestern Assay Provider: David Mangelsdorf,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2026
Entry Details US Patent

TargetBcl-2-like protein 1(Human)
Abbvie

US Patent
LigandChemical structure of BindingDB Monomer ID 540528BDBM540528(US20260028356, Example 15)
Affinity DataKi:  13.9nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Affiliation: UT Southwestern Assay Provider: David Mangelsdorf,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2026
Entry Details US Patent