BDBM540536 US11261186, Example 472

SMILES C[C@H]%10CCC(CNc9ccc(S(=O)(=O)NC(=O)c5ccc(N4CCN3CC2=C(c1ccc(Cl)cc1)CC(C)(C)C[C@H]2OCCCOC[C@@H]3C4)cc5N8CCCOc7nc6[nH]ccc6cc78)cc9[N+](=O)[O-])OC%10

InChI Key InChIKey=LABNFSIJSFWWFK-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 540536   

TargetApoptosis regulator Bcl-2(Human)
Abbvie

US Patent
LigandChemical structure of BindingDB Monomer ID 540536BDBM540536(US20260028356, Example 23)
Affinity DataKi:  0.634nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Affiliation: UT Southwestern Assay Provider: David Mangelsdorf,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2026
Entry Details US Patent

TargetBcl-2-like protein 1(Human)
Abbvie

US Patent
LigandChemical structure of BindingDB Monomer ID 540536BDBM540536(US20260028356, Example 23)
Affinity DataKi:  29.7nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Affiliation: UT Southwestern Assay Provider: David Mangelsdorf,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2026
Entry Details US Patent