BDBM540540 US11261186, Example 476

SMILES CC1(C)CC(c2ccc(Cl)cc2)=C2CN3CCN(c4ccc(C(=O)NS(=O)(=O)c5ccc(NC[C@@H]6CCC(O)CO6)c([N+](=O)[O-])c5)c(N5CCCOc6nc7[nH]ccc7cc65)c4)CC3C3OCCCC3[C@@H]2C1

InChI Key InChIKey=QCUHUSAQGSRTRI-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 540540   

TargetApoptosis regulator Bcl-2(Human)
Abbvie

US Patent
LigandChemical structure of BindingDB Monomer ID 540540BDBM540540(US20260028356, Example 27)
Affinity DataKi:  1.72nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Affiliation: UT Southwestern Assay Provider: David Mangelsdorf,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2026
Entry Details US Patent

TargetBcl-2-like protein 1(Human)
Abbvie

US Patent
LigandChemical structure of BindingDB Monomer ID 540540BDBM540540(US20260028356, Example 27)
Affinity DataKi:  7.41nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Affiliation: UT Southwestern Assay Provider: David Mangelsdorf,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2026
Entry Details US Patent