BDBM541455 US11267811, Example 46

SMILES OC[C@H]1O[C@H]([C@H](O)[C@H]([C@H]1O)n1cc(nn1)-c1cc(F)c(F)c(F)c1)c1ncnn1-c1ccc2ncsc2c1

InChI Key InChIKey=ISLMBWBWRXOTIJ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 541455   

TargetGalectin-3(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM541455(US11267811, Example 46)
Affinity DataIC50: 37nMAssay Description:Inhibition of human Galectin-3More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetGalectin-3(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM541455(US11267811, Example 46)
Affinity DataIC50: 40nMAssay Description:The Gal-3 assays were performed in 384 white Opti plates in three replicates at room temperature with gentle shaking at 250-300 rpmFrom the original ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2022
Entry Details
US Patent

TargetGalectin-3(Mouse)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM541455(US11267811, Example 46)
Affinity DataIC50: 939nMAssay Description:Inhibition of mouse Galectin-3More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed