BDBM541460 US11267811, Example 51

SMILES Cc1nc2cc(Cl)c(cc2s1)-n1ncnc1[C@@H]1O[C@H](CO)[C@H](O)[C@@H]([C@H]1O)n1cc(nn1)-c1cc(F)c(F)c(F)c1

InChI Key InChIKey=KNXPPDTWTPNLAH-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 541460   

TargetGalectin-3(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM541460(US11267811, Example 51)
Affinity DataIC50: 70nMAssay Description:The Gal-3 assays were performed in 384 white Opti plates in three replicates at room temperature with gentle shaking at 250-300 rpmFrom the original ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2022
Entry Details
US Patent

TargetGalectin-3(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM541460(US11267811, Example 51)
Affinity DataIC50: 71nMAssay Description:Inhibition of human Galectin-3More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetGalectin-3(Mouse)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM541460(US11267811, Example 51)
Affinity DataIC50: 1.31E+3nMAssay Description:Inhibition of mouse Galectin-3More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed